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What is Apoptosis ?

What is Apoptosis ?

In every second cell dies and replaces perhaps one million cells per second in our body. Apoptosis is the form of the death of the cell or cell suicide which is An Essential Part of Life. It is also referred to programmed cell death. The cell’s DNA gives the biochemical instructions for the Apoptosis process which is just like other complex cellular processes. For maintaining the health of the body, Apoptosis plays a crucial role. It eliminates unnecessary, unhealthy and old cells during the process. When this process of cell death is interrupted or does not work correctly, cells that should be eliminated may continuously grow and become the cancerous tumor.

Apoptosis can be divided into two pathways these are:
Intrinsic pathway: when there is a DNA damage inside a cell and it gets a signal from its genes or proteins to destroy itself is called the intrinsic pathway.
Extrinsic pathway: cells get the signal from another cell of the organism to destroy the particular cells. The apoptosis which follows this kind of pathway is called the extrinsic pathway.

An apoptotic cell can be characterized by:

  • Condensation of chromatin
  • Membrane blebbing (or formation of irregular bulges)
  • Cell shrinkage
  • The disintegration of the nuclear envelope

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